In addition to the Mae Sot to Mo Chit route Bangkok), buses also travel directly to Mae Sai, via Chiang Mai and Chiang Rai. Departure times from Mae Sot are 6am and 8am from the main bus terminal. Tickets can usually be purchased without problems at the station on the morning of departure. Ask your guesthouse to arrange an early morning tuk tuk to the station. The ticket booth opens at 5:30 am. The Green Bus direct route to Chaing Mai has moved its ticket office to a building on the Asia Highway just to the west of 105 North.
There are two classes of buses, but both are very clean and spacious and also include a free or 10bt lunch voucher. Total travel time to Chiang Mai is about 6 hours; Chiang Rai, 9 hours. Tickets are 250/350bt and 350/500bt, respectively, and depending on the bus class. Green Bus buses from Chiang Mai to Mae Sot depart daily at 11:45 2nd class and 13:10 1st class.
As of early 2009, bus lines have also opened for daily travel to Laem Ngop Ko Chang and Mukdahan. The company who runs this service is Phetprasert.
The Laem Ngop bus travels south towards Bangkok, veering east before entering the city, and then traveling along the coast via Chonburi and Rayong. The travel time from Mae Sot to the ferry departure point for Koh Chang is around 16 hours and the ticket costs 750 bt.
The Mukdahan bus makes station-only stops, including Sukhothai, Phitsanulok, and Khon Kaen. The company claims that total travel time is 12-14 hours.
Another way to leave Mae Sot is to catch the minibus to Tak to connect to onward buses. These leave throughout the day around every 40 minutes from the old market area which is over the bridge from Green Guesthouse. The trip to Tak takes around one and a half hours and costs 78 ฿.
Mae Hong Son
Sukhothai
Tak